High-paying nursing jobs in Mississauga
Nursing involves the care of individuals, families, and communities to maintain or improve their health. Nurses play critical roles in healthcare settings, providing direct patient care, education, and support. They utilize skills such as empathy, communication, and clinical expertise to achieve positive health outcomes.
The 814 nursing jobs listed below pay well, with salaries between $30.75 and $52.45 per hour. Registered Practical Nurse, Registered Nurse and Nurse Practitioner are among the most popular high-paying roles in Mississauga, ON.
Job title
Updated Sep. 24, 2026
Job title
Mississauga, ON
Ontario
Job openings (Mississauga)
Nurse Practitioner
Mississauga
$64.42
per hour
Ontario
$69.93
per hour
Registered Nurse - Operating Room
Mississauga
$52.45
per hour
Ontario
$46.13
per hour
Registered Nurse
Mississauga
$42.97
per hour
Ontario
$46.47
per hour
Nurse
Mississauga
$40.18
per hour
Ontario
$35.15
per hour
Clinical Lead Nurse
Mississauga
$72,179
per year
Ontario
$116,620
per year
Registered Practical Nurse
Mississauga
$30.75
per hour
Ontario
$34.65
per hour
Job descriptions below are for educational purposes. Please refer to the employer's job description for complete details.
-
Nurse Practitioner
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Please refer to the employers job description for complete details.
Nurse Practitioners assess and manage patient health, prescribe treatments, and provide counselling across settings. They need clinical assessment expertise, knowledge of Canadian healthcare standards, and strong communication skills.
See 58 jobsAverage salary
Mississauga
$64.42 per hourOntario
$69.93 per hourSkills
- Nursing
- Patient care
- EMR systems
- Communication skills
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Registered Nurse - Operating Room
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Please refer to the employers job description for complete details.
Registered Nurses - Operating Room coordinate surgical preparations, monitor patient safety during procedures, and maintain sterile environments. They need expertise in surgical nursing, knowledge of intraoperative protocols, and proficiency in critical thinking under pressure.
See 42 jobsAverage salary
Mississauga
$52.45 per hourOntario
$46.13 per hourSkills
- Nursing
- Patient care
- Medical terminology
-
Registered Nurse
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Please refer to the employers job description for complete details.
Registered Nurses provide patient care, administer treatments, and coordinate with healthcare teams. They need clinical nursing expertise, familiarity with Canadian healthcare protocols, and strong communication skills to support diverse patient needs.
See 266 jobsAverage salary
Mississauga
$42.97 per hourOntario
$46.47 per hourSkills
- Nursing
- Patient care
-
Nurse
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Please refer to the employers job description for complete details.
Nurses provide patient care, administer treatments, and coordinate with healthcare teams to monitor recovery. They need nursing licensure, strong clinical assessment skills, and compassionate communication to support diverse patient needs effectively.
See 50 jobsAverage salary
Mississauga
$40.18 per hourOntario
$35.15 per hourSkills
- Nursing
- Patient care
- Medical terminology
-
Clinical Lead Nurse
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Please refer to the employers job description for complete details.
Clinical Lead Nurses oversee nursing teams, coordinate patient care plans, and ensure clinical standards are met. They need expert nursing knowledge, skill in team leadership, and familiarity with healthcare protocols to guide quality practices effectively.
See 28 jobsAverage salary
Mississauga
$72,179 per yearOntario
$116,620 per yearSkills
- Acute care
- Computer skills
- Leadership
- Organizational skills
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Registered Practical Nurse
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Please refer to the employers job description for complete details.
Registered Practical Nurses provide hands-on patient care, administer prescribed treatments, and monitor health changes. They need clinical knowledge, medication administration skills, and understanding of care plans to support patients effectively in medical settings.
See 370 jobsAverage salary
Mississauga
$30.75 per hourOntario
$34.65 per hourSkills
- Vital signs
- Geriatrics
- English