High-paying nursing jobs in Mississauga
Nursing involves the care of individuals, families, and communities to maintain or improve their health. Nurses play critical roles in healthcare settings, providing direct patient care, education, and support. They utilize skills such as empathy, communication, and clinical expertise to achieve positive health outcomes.
The 696 nursing jobs listed below pay well, with salaries between $31.05 and $42.60 per hour. Registered Practical Nurse, Registered Nurse and Nurse Practitioner are among the most popular high-paying roles in Mississauga, ON.
Job title
Updated Oct. 28, 2026Nurse Practitioner
Mississauga
Ontario
Registered Nurse - Emergency Room
Mississauga
Ontario
Registered Nurse - Icu
Mississauga
Ontario
Registered Nurse - Operating Room
Mississauga
Ontario
Registered Nurse
Mississauga
Ontario
Nurse
Mississauga
Ontario
Registered Nurse - Palliative Care
Mississauga
Ontario
Nurse Injector
Mississauga
Ontario
Clinical Lead Nurse
Mississauga
Ontario
Registered Practical Nurse
Mississauga
Ontario
Job descriptions below are for educational purposes. Please refer to the employer's job description for complete details.
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Nurse Practitioner
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Nurse Practitioners assess and manage patient health, prescribe treatments, and provide counselling across settings. They need clinical assessment expertise, knowledge of Canadian healthcare standards, and strong communication skills.
See jobsAverage salary
Mississauga
$63.93 per hourOntario
$69.96 per hourSkills
- Nursing
- Patient care
- EMR systems
- Communication skills
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Registered Nurse - Emergency Room
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Registered Nurses - Emergency Room provide urgent patient assessment, deliver stabilizing treatments, and coordinate rapid care in critical situations. They need proficiency in trauma nursing, knowledge of emergency protocols, and strong communication under pressure.
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Mississauga
$62.62 per hourOntario
$49.26 per hourSkills
- Nursing
- Patient care
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Registered Nurse - Icu
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Registered Nurse - ICU professionals manage critical patient care, monitor vital signs, and coordinate emergency responses. They need expertise in advanced life support, familiarity with ICU technology, and strong clinical judgement under pressure.
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Mississauga
$58.71 per hourOntario
$49.82 per hourSkills
- Nursing
- Patient care
- ICU experience
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Registered Nurse - Operating Room
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Registered Nurses - Operating Room coordinate surgical preparations, monitor patient safety during procedures, and maintain sterile environments. They need expertise in surgical nursing, knowledge of intraoperative protocols, and proficiency in critical thinking under pressure.
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Mississauga
$50.86 per hourOntario
$46.36 per hourSkills
- Nursing
- Patient care
- Medical terminology
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Registered Nurse
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Registered Nurses provide patient care, administer treatments, and coordinate with healthcare teams. They need clinical nursing expertise, familiarity with Canadian healthcare protocols, and strong communication skills to support diverse patient needs.
See jobsAverage salary
Mississauga
$43.43 per hourOntario
$46.44 per hourSkills
- Nursing
- Patient care
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Nurse
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Nurses provide patient care, administer treatments, and coordinate with healthcare teams to monitor recovery. They need nursing licensure, strong clinical assessment skills, and compassionate communication to support diverse patient needs effectively.
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Mississauga
$42.60 per hourOntario
$35.67 per hourSkills
- Nursing
- Patient care
- Medical terminology
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Registered Nurse - Palliative Care
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Registered Nurse - Palliative Care professionals manage symptom relief, provide emotional support, and coordinate with families during end-of-life phases. They need expertise in pain management, understanding of palliative principles, and strong communication skills.
See jobsAverage salary
Mississauga
$40.29 per hourOntario
$38.79 per hour -
Nurse Injector
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Mississauga
$39.86 per hourOntario
$38.33 per hour -
Clinical Lead Nurse
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Clinical Lead Nurses oversee nursing teams, coordinate patient care plans, and ensure clinical standards are met. They need expert nursing knowledge, skill in team leadership, and familiarity with healthcare protocols to guide quality practices effectively.
See jobsAverage salary
Mississauga
$71,917 per yearOntario
$117,002 per yearSkills
- Acute care
- Computer skills
- Leadership
- Organizational skills
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Registered Practical Nurse
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Please refer to the employers job description for complete details.
Registered Practical Nurses provide hands-on patient care, administer prescribed treatments, and monitor health changes. They need clinical knowledge, medication administration skills, and understanding of care plans to support patients effectively in medical settings.
See jobsAverage salary
Mississauga
$31.05 per hourOntario
$34.61 per hourSkills
- Long term care experience
- Vital signs
- Geriatrics
- English