Medical Research Associate jobs in Mississauga, ON

About Us:

QurCan Therapeutics is a forward-thinking biotech company harnessing next-generation nanoparticle technology for the advancement of genetic and biological therapeutics. We are excited to welcome motivated and innovative minds to our R&D site in Toronto. We're currently seeking a highly motivated Associate scientist with a MSc/PhD in neuroscience & molecular biology to be part of our dynamic product development team.

Position Overview:

As a Molecular Biology Research Associate/Associate Neuroscientist, you will contribute your expertise to our cutting-edge research in nucleic acid assay development. Collaborating within a cross-disciplinary team of scientists, you will tackle complex challenges in designing and conducting molecular biology, cell-based, and animal studies to evaluate therapeutic efficacy, safety, biodistribution, and mechanisms of action.

Tasks and Responsibilities:

- Design, plan, and execute in vitro and in vivo studies supporting the development of RNA therapeutics

- Evaluate novel siRNA and mRNA-based formulations using fluorescent and immunology-based assays in vitro and ex vivo
- Perform molecular and cellular biology assays to assess changes in gene and protein expression

- Conduct techniques such as quantitative PCR, RT-qPCR, Western blotting, ELISA, immunocytochemistry, and related analytical assays.

- Implementation and refinement of protocols.

- Conducting RNA/DNA sequencing

- Conducting cell-based assays, which involve the cultivation and seeding of cell lines and primary cells, as well as executing transfection experiments

- Maintenance of meticulous lab records, regular data analysis, and contribution to shared records.

- Effective management of critical reagent inventories such as cells, media, and cytokines.

- Plan and conduct preclinical animal studies to evaluate therapeutic efficacy, safety, tolerability, biodistribution, and pharmacodynamic responses.

-Able to create high-throughput experimental designs, address technical challenges, analyze data, and communicate findings to teams effectively

Requirements:

- M.S./Ph.D. degree neuroscience and molecular biology

- Demonstrated experience evaluating gene and protein expression using relevant molecular and biochemical techniques.

- Having years of experience in siRNA and mRNA modifications and in-vitro studies

- Strong experience in cell culture, cell treatments, gene expression and silencing assays in mammalian cells lines.

- Experience processing tissues and assessing molecular, cellular, or histological changes.

- Strong scientific writing, data interpretation, presentation, and communication skills.

Preferred:

- MSc/PhD, recently graduated from a Canadian academic institution, with high enthusiasm in new scientific discoveries and trends in the biotechnology field.

Why Join Us:

- Be at the forefront of pioneering research in the biotech industry.

- Collaborate with a diverse team of experts.

- Opportunity for professional growth and development.

- Contribute to shaping the future of genetic and biological therapeutics.

Application Process:

If you are enthusiastic about being part of our innovative journey, please apply by submitting your resume and cover letter through our online application portal. We appreciate your interest in QurCan Therapeutics; only shortlisted candidates will be contacted.

Job Type: Full-time

Pay: From $70,000.00 per year

Application question(s):

• Have you done gene expression/silencing experiments in mammalian cell lines?
• Do you have a PhD degree in neuroscience, Cellular and Molecular Biology, genetics, or relevant fields?
• Do you have in-vivo work experience?
• Are you graduated from a Canadian institution?
• How many years have passed since your graduation?
• Do you have more than 3 years of cell culture experience using human/murine cells lines?

Education:

• Master's Degree (required)

Experience:

• Laboratory: 4 years (preferred)

Work Location: In person