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Job Post Details

Associate Scientist - job post

Lifecycle Sciences Inc.
Richmond, BC V6V 1Y4
$70,000–$85,000 a year - Full-time
Responded to 75% or more applications in the past 30 days, typically within 1 day.

Job details

Pay

  • $70,000–$85,000 a year

Job type

  • Full-time

Location

Richmond, BC V6V 1Y4

Benefits

Pulled from the full job description

  • On-site parking

Full job description

Job Title: Associate Scientist, mRNA, LNP & Stem Cell Biology

Company: Lifecycle Sciences Inc.

Location: Richmond, BC (On-site)

Job Type: Full-time

The Role We are seeking a highly motivated and technically skilled Associate Scientist to join our R&D team. This is a hands-on, wet-lab-focused role where you will be instrumental in executing our experiments. The ideal candidate brings specific, demonstrable expertise in mRNA synthesis (ideally hands-on experience with IVT), Lipid Nanoparticle (LNP) formulation, and mammalian stem cell culture.

You will work directly with our lead scientists to develop cutting-edge cellular reprogramming protocols and prepare formulations for both in vitro analysis and upcoming downstream studies.

Key Responsibilities

  • mRNA Synthesis & Handling: Design, synthesize, and purify mRNA using in vitro transcription (IVT) and optimize protocols for maximum stability and expression.
  • LNP Formulation: Formulate, optimize, and characterize LNPs for the delivery of mRNA payloads (utilizing microfluidics, DLS, etc.).
  • Cell Culture: Cultivate and maintain primary mammalian cell lines.
  • Administration & Transfection: Execute in vitro cell transfections and assist with the preparation and administration of mRNA/LNP and cellular payloads.
  • Analytical Assays: Perform downstream cellular and molecular analyses to validate experiments, utilizing multi-color flow cytometry, live-cell imaging, qPCR, and ELISA.
  • Documentation: Maintain meticulous, GLP-compliant laboratory notebooks, draft detailed SOPs, and compile data for Health Canada regulatory briefs.

Qualifications & Skills

  • Minimum of a M.Sc. in Molecular Biology, Bioengineering, Biochemistry, Cellular Biology, or a closely related discipline.
  • Demonstrated, hands-on laboratory experience with mRNA synthesis and LNP formulation and physicochemical characterization is strictly required.
  • Strong proficiency in mammalian cell culture; specific experience handling primary stem cells is a massive asset.
  • Familiarity with advanced lab equipment (e.g., qPCR and PCR, ELISA, microfluidics mixers, TFF Systems, DLS, Zeta-potential analyzer, HPLC, Capillary Electrophoresis, flow cytometer).
  • Understanding of GLP guidelines and standard industry protocols.
  • An entrepreneurial mindset: you thrive in a fast-paced startup environment, are highly adaptable, and take ownership of your wet-lab bench.

Pay: $70,000.00-$85,000.00 per year

Benefits:

  • On-site parking

Application question(s):

  • Do you have experience with synthesizing mRNA?
  • Do you have experience in mRNA quality control?
  • Do you have experience with mRNA delivery methods?

Work Location: In person

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